FDA Clears Brentuximab Combo for Advanced Large B-Cell Lymphoma Treatment

FDA Clears Brentuximab Combo for Advanced Large B-Cell Lymphoma Treatment

The U.S. Food and Drug Administration (FDA) has given the green light to a new combination therapy for adults suffering from specific types of relapsed or hard-to-treat large B-cell lymphomas (LBCL) who are not suitable candidates for stem cell transplants or CAR-T therapy. This innovative treatment consists of brentuximab vedotin (Adcetris), lenalidomide, and rituximab (BV+R2). It specifically targets types of LBCL such as diffuse large B-cell lymphoma (DLBCL), high-grade B-cell lymphoma, and DLBCL that arises from slower-growing lymphoma.

FDA Approves ADCETRIS® Combination Therapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma

FDA Approves ADCETRIS® Combination Therapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma

The U.S. Food and Drug Administration (FDA) has approved a new treatment regimen that includes Pfizer’s ADCETRIS® (brentuximab vedotin) for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). This is an important development as it provides a new option for individuals who have not responded to at least two previous therapies and are not candidates for more aggressive treatments such as stem cell transplantation or CAR T-cell therapy.

FDA Expands IZERVAY™ Approval for Long-Term Geographic Atrophy Treatment

FDA Expands IZERVAY™ Approval for Long-Term Geographic Atrophy Treatment

The US FDA has approved a new expanded label for Astellas Pharma’s IZERVAY™ (avacincaptad pegol intravitreal solution) to treat geographic atrophy (GA) due to age-related macular degeneration (AMD) long-term. The expansion provides physicians and patients with more options for treating this progressive and chronic eye disease, which can cause irreversible vision loss.

SGLT-2 Inhibitors and Left Ventricular Function in Type 2 Diabetes

SGLT-2 Inhibitors and Left Ventricular Function in Type 2 Diabetes

The study, titled “The protective effect of sodium-glucose cotransporter-2 inhibitor on left ventricular global longitudinal strain in patients with type 2 diabetes mellitus according to disease duration,” investigates the impact of SGLT2 inhibitors on heart function in type 2 diabetes patients.