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Causal Effect Between Total Cholesterol and HDL Cholesterol as Risk Factors for Chronic Kidney Disease: A Mendelian Randomization Study

Causal Effect Between Total Cholesterol and HDL Cholesterol as Risk Factors for Chronic Kidney Disease: A Mendelian Randomization Study

The MR study indicate causal effects between TC, HDL-C and CKD. Decreased TC and elevated HDL-C may reduce the incidence of CKD but need to be further confirmed by using a genetic and environmental approach.

The Correlation Between Lipoprotein(a) and Coronary Atherosclerotic Lesion is Stronger than LDL‑C, when LDL‑C is Less than 104 mg/dL

The Correlation Between Lipoprotein(a) and Coronary Atherosclerotic Lesion is Stronger than LDL‑C, when LDL‑C is Less than 104 mg/dL

The study described that Lp(a) was the risk factor of CAHD in patients with LDL-C < 100 mg/dL. The correlation between Lp(a) and Gensini was influenced by LDL-C concentration, and the correlation was stronger than LDL-C when LDL-C < 104 mg/dL.

Left Ventricular Summit Arrhythmias with an Abrupt V3 Transition: Anatomy of the Aortic Interleaflet Triangle Vantage Point

Left Ventricular Summit Arrhythmias with an Abrupt V3 Transition: Anatomy of the Aortic Interleaflet Triangle Vantage Point

The study described the prevalence, characteristics, and outcomes of a new distinct electrocardiographic pattern of outflow tract ventricular arrhythmias (OTVA) with left bundle branch morphology and abrupt transition in lead V3 (ATV3) that localizes to the septal margin of the LV summit.

Should all Patients with Hypertension Be Worried about Developing Severe Coronavirus Disease 2019 (COVID-19)?

Should all Patients with Hypertension Be Worried about Developing Severe Coronavirus Disease 2019 (COVID-19)?

A novel study reveals predictive factors for developing severe COVID-19 that can be used by physicians to identify high risk hypertensive COVID-19 cases and determine appropriate treatment approach to achieve best possible clinical outcomes.

Phenotypic Clustering of Dilated Cardiomyopathy Patients Highlights Important Pathophysiological Differences

Phenotypic Clustering of Dilated Cardiomyopathy Patients Highlights Important Pathophysiological Differences

The present study identified four different DCM phenogroups associated with significant differences in clinical presentation, underlying molecular profiles and outcome, paving the way for a more personalized treatment approach.

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