People with diabetes or prediabetes face an elevated risk of developing various cardiovascular conditions, including heart disease, stroke, and congestive heart failure. One crucial factor contributing to this increased risk is how well the body utilizes insulin, which can be measured using the estimated glucose disposal rate (eGDR). A lower eGDR score indicates a poorer ability to process insulin and is associated with a higher likelihood of developing heart-related complications.

Recent studies have shown that eGDR is a more accurate predictor of heart disease risk in individuals with diabetes or prediabetes compared to other commonly used tests. For example, tests that measure insulin resistance through different calculations have been traditionally used, but eGDR has proven to offer superior predictive value when it comes to cardiovascular risks.
This finding highlights the potential of eGDR as a valuable tool for early identification of individuals at a heightened risk for heart disease. By integrating eGDR into routine assessments for patients with diabetes or prediabetes, healthcare providers could pinpoint those who would benefit most from preventative measures, such as lifestyle changes or medical interventions.

Ultimately, eGDR presents a promising opportunity for improving risk assessment in this high-risk group, allowing for timely intervention that could help prevent the onset of severe cardiovascular events and improve long-term health outcomes.

Source: cardiab.biomedcentral.com/articles/10.1186/s12933-024-02570-y